Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation

Article type: Research Article

Authors: Esmer, Ahmet Cem^a | Tazeoglu, Deniz^a; | Dag, Ahmet^a

Affiliations: [a] Department of Surgical Oncology, Faculty of Medicine, Mersin University, Mersin, Turkey

Correspondence: [*] Corresponding author: Deniz Tazeoglu, Department of General Surgery, Faculty of Medicine, Mersin University, Ciftlikkoy Mah. Mersin University Ciftlikkoy Campus, 33110 Yenişehir/Mersin, Turkey. Tel.: +90 505 743 2125;E-mail: [email protected]. ORCIDs:http://orcid.org/0000-0001-8279-186X (A.C. Esmer); http://orcid.org/0000-0002-5947-8653 (D. Tazeoglu); http://orcid.org/0000-0002-1120-3773 (A. Dag)

Abstract: BACKGROUND:Pseudoangiomatous stromal hyperplasia is a rare benign breast stromal proliferative lesion of the breast. Clinical presentation ranges from rapidly growing mass to incidental identification in routine screening. This difference in manifestation and its rarity makes it difficult to be a standard treatment protocol. Therefore, we aimed to share our clinical experience in Pseudoangiomatous stromal hyperplasia. METHODS:The files of patients who underwent core biopsy or surgical excision due to a breast mass and resulted in pseudoangiomatous stromal hyperplasia between January 2013 and December 2021 were included in the study. RESULTS:17 patients with a median age of 37 (22–68) were found Pseudoangiomatous stromal hyperplasia confirmed by surgical excision or core biopsy. Chosen treatment option was observation in 8 patients (47.1%), while surgical excision was used in 9 (52.9%) patients. The mean follow-up period was 55.24 ± 26.72 (13–102) months. None of the patients observed the Malignant transformation during the follow-up period. CONCLUSION:For Pseudoangiomatous Stromal Hyperplasia of the breast, surgical excision with clean margins or close follow-up after diagnosis confirmation by tissue biopsy is sufficient. Pseudoangiomatous Stromal Hyperplasia is not a risk factor for developing breast cancer.

Keywords: Breast, core biopsy, pseudoangiomatous stromal hyperplasia, surgical excision

DOI: 10.3233/BD-220070

Journal: Breast Disease, vol. 42, no. 1, pp. 115-119, 2023