Primary amyloidosis of the breast excised using an oncoplastic reduction approach

Article type: Case Report

Authors: Upadhyaya, Siddhi N.^a | Fan, Betty^a | Bernard, Steven L.^b | Samaras, Christy J.^c | Valente, Stephanie A.^a;

Affiliations: [a] Department of General Surgery, Division of Breast Services, Cleveland Clinic, Cleveland, OH, USA | [b] Department of Plastic and Reconstructive Surgery, Cleveland Clinic, Cleveland, OH, USA | [c] Department of Hematology/Oncology, Cleveland Clinic, Cleveland, OH, USA

Correspondence: [*] Corresponding author: Stephanie A. Valente, Cleveland Clinic, 9500 Euclid Ave, A80, Cleveland, OH 44195, USA. Tel.: 216 444 0769; Fax: 216 445 4048; E-mail: [email protected]

Abstract: We present a case of surgical removal of primary amyloidosis of the breast utilizing an oncoplastic reduction pattern technique. Primary amyloidosis of the breast is a very rare benign disease characterized by accumulation of insoluble amyloid protein. Biopsy is required for definitive diagnosis, and surgical removal of the mass with clear margins is the main treatment for primary amyloidosis. Oncoplastic reduction pattern technique allows for removal of large breast lesions and correction of the resulting defect by combining the extirpative principles of surgical oncology with the aesthetic principles of breast reduction surgery.

Keywords: Amyloidosis, breast mass, oncoplastic

DOI: 10.3233/BD-190424

Journal: Breast Disease, vol. 39, no. 2, pp. 101-104, 2020