Insight out: Advances in understanding metabolism achieved by high-throughput mass spectrometry

Article type: Research Article

Authors: Fendt, Sarah-Maria | Stephanopoulos, Gregory^;

Affiliations: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

Note: [] Corresponding author: Gregory Stephanopoulos, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. E-mail: [email protected]

Abstract: Metabolism is the functional interconnection between the genome, transcriptome and proteome with the cellular phenotype. Thus, understanding metabolism is of great interest in various research areas ranging from metabolic engineering to the biomedical research field. Here we frame, based on recent advances in elucidating various metabolic nodes, a global perspective of our current understanding of metabolism.

Keywords: Metabolism, genome, proteome, transcriptome, high-throughput mass spectrometry

DOI: 10.3233/BSI-120032

Journal: Biomedical Spectroscopy and Imaging, vol. 2, no. 1, pp. 1-8, 2013