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Brain Reactions Caused by Administration of Antigen

Article type: Research Article

Authors: Perekrest, S.V. | Novikova, N.S. | Korneva, E.A.

Affiliations: Department of General Pathology and Pathophysiology, Institute of Experimental Medicine NWB RAMS, Saint-Petersburg, Russia

Note: [] Correspondence to: S.V. Perekrest, Department of General Pathology and Pathophysiology, Institute of Experimental Medicine NWB RAMS. 197376 Acad. Pavlova str., 12. Acad. Saint-Petersburg, Russia. Tel.: +7(812)2340764; Fax: +7(812)2349493; E-mail: [email protected]

Keywords: Neuro-immune interactions, antigen, hypothalamus

DOI: 10.3233/NIB-2011-003

Journal: Advances in Neuroimmune Biology, vol. 1, no. 1, pp. 25-37, 2011

Published: 2011
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Abstract

The present review deals with the reactions taking place in the central nervous system after antigen administration. The activation of brain cells and the involvement of various neurotransmitter systems after applying various antigens are described. The possible pathways of signal transduction from immune cells to the central nervous system (CNS) are analyzed. The knowledge acquired about the activation pattern of different neuron populations could help to clarify the mechanisms of immune-to-brain communication.

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