Infectious mononucleosis due to Epstein Barr virus infection presenting as life threatening thrombocytopenic bleeding

Article type: Research Article

Authors: Nandi, M. | Das, M.K.

Affiliations: Department of Pediatrics,NRS Medical College, Kolkata, India | Department of Pediatrics, IPGME&R, Kolkata, India

Note: [] Corresponding author: Madhumita Nandi, 6/6, Naren Sarkar Road, Barisha Kolkata-700008, India. Tel.: +91 9433166790; E-mail: [email protected]

Abstract: Acute onset transient thrombocytopenia is a known complication of infectious mononucleosis due to Epstein Barr virus infection. Infectious mononucleosis presenting with severe thrombocytopenia resulting in life threatening bleeding is rare, and may cause diagnostic confusion with more sinister conditions like acute leukemia. We report one such case of severe bleeding in association with Epstein Barr virus infection in a previously healthy adolescent girl and discuss the possible mechanisms of thrombocytopenia in infectious mononucleosis.

Keywords: Infectious mononucleosis, thrombocytopenia

DOI: 10.3233/JPI-140438

Journal: Journal of Pediatric Infectious Diseases, vol. 9, no. 4, pp. 193-195, 2014