Affiliations: [a] Department of Otorhinolaryngology – Head and Neck Surgery, Turku University Hospital and University of Turku, Turku, Finland | [b] BioCity, Turku Biomaterials Research Program, Turku Clinical Biomaterials Centre – TCBC, Finland | [c] Process Chemistry Centre, Laboratory of Inorganic Chemistry, Åbo Akademi University, Finland | [d] Department of Biomaterials Science and Turku Clinical Biomaterials Centre – TCBC, Institute of Dentistry, University of Turku, and City of Turku Welfare Division, Oral Health Care, Turku, Finland
Correspondence:
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Corresponding author: Jussi Sarin, Department of Otorhinolaryngology – Head and Neck Surgery, Turku University Hospital, Kiinamyllynkatu 4-8, FI-20521, Turku, Finland. E-mail: [email protected].
Abstract: Bioactive glass (BG)-containing fiber-reinforced composite implants, typically screw-retained, have started to be used clinically. In this study, we tested the mechanical strength of composites formed by a potential implant adhesive of n-butyl-2-cyanoacrylate glue and BG S53P4 particles. Water immersion for 3, 10 or 30 days had no adverse effect on the compression strength. When cyanoacrylate glue-BG-composites were subjected to simulated body fluid immersion, the average pH rose to 7.52 (SD 0.066) from the original value of 7.35 after 7 days, and this pH increment was smaller compared to BG particle-group or fibrin glue-BG-composite group. Based on these results n-butyl-2 cyanoacrylate glue, by potentially producing a strong adhesion, might be considered a possible alternative for fixation of BG S53P4 containing composite implants. However, the mechanical and solubility properties of the cyanoacrylate glue may not encourage the use of this tissue adhesive with BG particles.
